Insulin resistance is manifested by the decreased sensitivity of peripheral tissues to insulin. Insulin facilitates the glucose transport from blood to cells. Insulin is essential for the intra-cellular transport of glucose into insulin-dependent tissues such as muscle and adipose tissue, otherwise the glucose deficit in cells will occur. In this case the glycogenesis (the process of glucose synthesis from fatty acids) and glycogenolysis processes (glycogen breakdown with subsequent glucose release) will be activated. Transported into blood, the glucose will increase glycaemia level. If a person leads sedentary lifestyle, therefore, muscles do not work and do not burn glucose, losing the habit of utilizing it. Glucose unclaimed by muscles results in increased blood glucose level.
The glucose transporter function is increased by insulin activity and active muscle work, therefore, the increased physical activity in diabetes II type results in decreased blood glucose level due to increased glucose uptake by muscles.
Sedentary lifestyle requires increased insulin secretion for balancing blood sugar level. Hyperinsulinemia increase the appetite and results in obesity.
High-calorie diet containing great amount of carbohydrates and fats aggravate the obesity. Person is going round in circles: hypodynamia – aggravated obesity – greater hypodynamia – aggravated obesity. The term visceral (abdominal) obesity defines excessive fat accumulation around the organs within the abdominal cavity is associated with obesity in insulin resistance conditions. Abdominal fat oxidize very quickly and may be dangerous due to the increased risk of atherosclerosis and cardiovascular diseases.
The glucose transporter function is increased by insulin activity and active muscle work, therefore, the increased physical activity in diabetes II type results in decreased blood glucose level due to increased glucose uptake by muscles.
Sedentary lifestyle requires increased insulin secretion for balancing blood sugar level. Hyperinsulinemia increase the appetite and results in obesity.
High-calorie diet containing great amount of carbohydrates and fats aggravate the obesity. Person is going round in circles: hypodynamia – aggravated obesity – greater hypodynamia – aggravated obesity. The term visceral (abdominal) obesity defines excessive fat accumulation around the organs within the abdominal cavity is associated with obesity in insulin resistance conditions. Abdominal fat oxidize very quickly and may be dangerous due to the increased risk of atherosclerosis and cardiovascular diseases.
